The
candidate theory of human aging here
is that the mTOR pathway limits life span and inhibition of this pathway might result in life extension.
A
cross-species pathway has been discovered
that allows interventions to lengthen
life in primitive organisms, C. elegans
nematode worms in this case. The pathway is related to the hypoxic response, how cells respond to protect themselves when there is insufficient oxygen. The candidate theory of aging in this case is keeping
the hypoxic response turned
on can contribute to longevity.