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•Type D cells are the
workhorses of day-to-day functioning and the key factors involved are insuring a good supply of them by
avoiding damage-related or
replicative senescence, taking care of their need for nutrition and a healthy intra-cellular environment, and making
sure that damaged or
proto-cancerous cells are eliminated through proper apoptosis. Also, it is important to assure that Type B and C cells are able
to differentiate properly to
provide a reliable continuing source of replacements for the Type D cells.
•The issues for Types B and C
cells include seeing that they are in sufficient supply and health so as to be able to differentiate into
Type D cells and making sure
that the differentiating option is readily available when needed. Other
issues for Types B and C cells are similar to those for Type D cells - preventing damage-related or replicative
senescence, and preventing
oncogenesis.
•In aged individuals there
are few if an active Type A cells around to replace Type B and C cells as they are lost, a
possible major reason for aging.
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